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respiratory failure انه هنا بشكل جديد

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مُساهمة من طرف mr 7oda الأربعاء مارس 10, 2010 12:16 am

Respiratory Failure





1- Definition


-
Respiratory failure is nearly any condition that affects breathing function or
the lungs themselves and can result in failure of the lungs to function
properly.

- is used to describe inadequate gas exchange
by the respiratory
system, with the result that arterial oxygen and/or carbon dioxide levels
cannot be maintained within their normal ranges.


- A
drop in blood oxygenation
is known as hypoxemia;
a rise in arterial carbon dioxide levels is called hypercapnia.



2-Respiratory
failure is divided into type I and type II.


  • Type
    I respiratory failure involves low oxygen, and normal or low carbon
    dioxide levels.
  • Type
    II respiratory failure involves low oxygen, with high carbon dioxide.




3-Pathophysiologic Mechanisms
in Acute Respiratory Failure

-The act of respiration
engages 3 processes:


(1) transfer of oxygen across the alveolus,


(2)
transport of oxygen to the tissues,


(3)
removal of carbon dioxide from blood into the alveolus and then into the
environment.


-Respiratory
failure may occur from malfunctioning of any of these processes.


-
In order to understand the pathophysiologic basis of acute respiratory failure,
an understanding of pulmonary gas exchange is essential.
-is used to describe inadequate gas exchange
by the respiratory
system, with the result that arterial oxygen and/or carbon dioxide levels
cannot be maintained within their normal ranges.



4-Causes of respiratory
failure
· Common causes of
type I (hypoxemic) respiratory failure


  • Chronic
    bronchitis and emphysema (COPD)

  • Pneumonia
  • Pulmonary
    edema

  • Pulmonary
    fibrosis

  • Asthma
  • Pneumothorax
  • Pulmonary
    embolism

  • Pulmonary
    arterial hypertension

  • Pneumoconiosis
  • Granulomatous
    lung diseases

  • Cyanotic
    congenital heart disease

  • Bronchiectasis
  • Adult
    respiratory distress syndrome

  • Fat
    embolism syndrome

  • Kyphoscoliosis
  • Obesity







· Common causes of type II (hypercapnic)
respiratory failure



  • Chronic
    bronchitis and emphysema (COPD)

  • Severe
    asthma

  • Drug
    overdose

  • Poisonings
  • Myasthenia
    gravis

  • Polyneuropathy
  • Poliomyelitis
  • Primary
    muscle disorders

  • Porphyria
  • Cervical
    cordotomy

  • Head
    and cervical cord injury

  • Primary
    alveolar hypoventilation

  • Adult
    respiratory distress syndrome

  • Myxedema
  • Tetanus







5-Symptoms of Respiratory failure


The list of medical symptoms mentioned in various sources
for Respiratory failure may include:










6-Imaging
Studies


  • Chest
    radiograph

    o Chest
    radiography is essential because it frequently reveals the cause of
    respiratory failure. However, distinguishing between cardiogenic and
    noncardiogenic pulmonary edema often is difficult.






  • Echocardiography
    o
    Echocardiography need not be performed routinely in all patients with
    respiratory failure. However, it is a useful test when a cardiac cause of
    acute respiratory failure is suspected.






Other
Tests


  • Patients
    with acute respiratory failure generally are unable to perform pulmonary function
    tests (PFTs). However, PFTs are useful in the evaluation of chronic
    respiratory failure.



    • Normal
      values of forced expiratory volume in one second (FEV1) and
      forced vital capacity (FVC) suggest a disturbance in respiratory control.

    • A
      decrease in FEV1
      -to-FVC ratio indicates airflow obstruction, whereas a reduction in both the
      FEV1 and FVC and maintenance of the FEV1
      -to-FVC ratio suggest restrictive lung disease.

    • Respiratory
      failure is uncommon in obstructive diseases when the FEV1 is
      greater than 1 L and in restrictive diseases when the FVC is more than L.



  • An
    ECG should be performed to evaluate the possibility of a cardiovascular
    cause of respiratory failure; it also may detect dysrhythmias resulting
    from severe hypoxemia and/or acidosis.





7-Complications


  • Pulmonary
    o Common
    pulmonary complications of acute respiratory failure include pulmonary embolism,
    barotrauma, pulmonary fibrosis, and complications secondary to the use of
    mechanical devices.





  • Cardiovascular
    o Common
    cardiovascular complications in patients with acute respiratory failure
    include hypotension, reduced cardiac output, arrhythmia, pericarditis, and
    acute myocardial infarction.





  • Gastrointestinal
    o The major
    gastrointestinal complications associated with acute respiratory failure
    are hemorrhage, gastric distention, ileus,
    diarrhea,
    and pneumoperitoneum.

    o Stress
    ulceration is common in patients with acute respiratory failure; the
    incidence can be reduced by routine use of antisecretory agents or mucosal
    protectants.




  • Infectious
    o Nosocomial
    infections, such as pneumonia, urinary tract infections, and catheter-related
    sepsis, are frequent complications of acute respiratory failure.





  • Renal
    o Acute renal
    failure and abnormalities of electrolytes and acid-base homeostasis are
    common in critically ill patients with respiratory failure.






  • Nutritional
    o These include
    malnutrition and its effects on respiratory performance and complications
    related to administration
    of enteral or parenteral nutrition.


    8-Medication

    -Diuretics
    First-line therapy generally
    includes a loop diuretic such as furosemide, which inhibits sodium
    chloride reabsorption
    in the ascending loop of Henle.





-Furosemide
(Lasix)
Administer loop diuretics IV
because this allows for both superior potency and a higher peak concentration
despite increased incidence of adverse effects, particularly ototoxicity.



-Nitroglycerin
(Nitro-Bid, Nitrol)

SL nitroglycerin and Nitrospray are particularly useful in the patient who
presents with acute pulmonary edema with a systolic blood pressure of at least
100 mm Hg.






-Analgesics

Morphine IV is an excellent adjunct in the management of acute pulmonary edema.
In addition to being both an anxiolytic and an analgesic, its most important
effect is venodilation, which reduces preload. Also causes arterial dilatation,
which reduces systemic
vascular resistance and may increase cardiac output.


-Morphine sulfate (Duramorph, Astramorph,
MS Contin)
DOC for narcotic analgesia due
to reliable and predictable effects, safety profile, and ease of reversibility with
naloxone. Morphine sulfate administered IV may be dosed in a number of ways and
commonly is titrated until desired effect is obtained.

-Inotropics
Principal inotropic agents
include dopamine, dobutamine

-Dopamine
(Intropin)
Stimulates both adrenergic and
dopaminergic receptors.

-Norepinephrine
(Levophed)
Used in protracted hypotension
following adequate fluid replacement. Stimulates beta1- and alpha-adrenergic receptors,
which in turn increases cardiac muscle contractility and heart rate

-Bronchodilators
These agents are an important component
of treatment in respiratory failure caused by obstructive lung disease.



-Corticosteroids


Have been shown to be effective in accelerating
recovery from acute COPD exacerbations and are an important anti-inflammatory
therapy in asthma

-Methylprednisolone
(Solu-Medrol, Depo-Medrol)
Usually given IV in ED for initiation of corticosteroid therapy, although PO should theoretically be equally efficacious.



9-Treatment






-Nearly all patients are given oxygen as
the first treatment.


-Then the underlying cause of respiratory
failure mustbe addressed. Antibiotics are used to fight a lung
infection; bronchodilators, like albuterol, and steroid therapy are commonly
prescribed for patients with asthma.
-Nurses and respiratory
therapists have a number of methods to help patients overcome respiratory
failure. These include:



  • Suctioning the lungs through
    a small plastic tube passed through the nose.

  • This treatment removes
    secretions from the airway that the patient is unable to cough up.

  • Postural drainage therapy,
    in which the patient's position is adjusted frequently to help secretions
    drain into the central airways.

  • Chest percussion and mechanical vibrators
    are also applied to help loosen deep secretions.

  • The patient is then encouraged to cough
    up the secretions; if the patient isn't strong enough to do this, they are
    suctioned out.

  • Deep-breathing exercises,
    which are often prescribed after the patient recovers, help strengthen the
    muscles that aid breathing. One technique has the patient breathe out
    against pursed lips to increase pressure in the airways, preventing them
    from collapsing. -A device called a volumetric incentive spirometer is also
    used to encourage deep breathing while giving visual feedback.

  • The patient inhales slowly through a
    plastic tube attached to a clear plastic cylinder; the cylinder contains a
    piston and a ball that rests on top of it.

  • Inhalation raises the
    ball; the patient has to inhale deeply enough to move it to a
    predetermined mark.



    أتمنى من قلبى أن الحصيله
    تنال
    اعجابكم
    وان شاء الله تستفيدوا منها
mr 7oda
mr 7oda
..
..

العمر : 33
تاريخ التسجيل : 01/11/2009

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مُساهمة من طرف ghonem الأربعاء مارس 10, 2010 9:24 pm


حصيلة رائعة يا مستر حوده

ويارب تستفادوا منها

كل حصيلة ونتم بخير
ghonem
ghonem
..
..

العمر : 34
العمل/الترفيه : القراءة
المزاج : يتغير دائما
تاريخ التسجيل : 05/07/2009

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مُساهمة من طرف mr 7oda الخميس مارس 11, 2010 10:40 am

شكرا يا غنيم على المرور
mr 7oda
mr 7oda
..
..

العمر : 33
تاريخ التسجيل : 01/11/2009

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مُساهمة من طرف أمنس السبت مارس 13, 2010 7:19 pm

بجد يا حوده مش عارفه اشكرك ازاى

يـــا مستر حـــوده

وافرت عليا كتير والله
avatar
أمنس
.
.

العمر : 34
تاريخ التسجيل : 23/12/2009

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مُساهمة من طرف Moza Alaa السبت مارس 13, 2010 9:25 pm



معلومات قيمة ومهمة جداااااااااااااااااااااا جداااااااااااااااااااااااااا


تسلم إيدك يا مستر حوده على المجهود الرااااااااااائع ده

وإلى الأمام إن شاء الله

ودى ثالث حصيلة وعقبال الباقى إن شاء الله

تقبل مرورى يا حوده

و زى ما قلت فى النهاية كلنا

واااااااااااااااااااااحد

Moza Alaa
Moza Alaa
..
..

العمر : 34
العمل/الترفيه : كورة القدم والفوتوشوب وتنس الطاولة
المزاج : تماموززززززززززززززززززز بالموزززززززززززززززززززز واللبنوززززززززززززززززززز
تاريخ التسجيل : 13/06/2009

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مُساهمة من طرف mr 7oda السبت مارس 13, 2010 9:26 pm

يا امنس لا شكر على واجب

اتمنى الاستفاده لكى


وشكرا على مرورك


وشكرا لك يا احمد على المرور

وطبعا الهدف منها هو المصلحه العامه

وكلنا واحديعنى عصبه مع بعضينا

واتمنى الاستفاده لكل من شاهدها ولو قدر بسيط


عدل سابقا من قبل mr 7oda في السبت مارس 13, 2010 9:52 pm عدل 3 مرات
mr 7oda
mr 7oda
..
..

العمر : 33
تاريخ التسجيل : 01/11/2009

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